Background. Previous assessments of technical difficulty and procedure time for endoscopic submucosal dissection (ESD) of gastric\nneoplasms did not take into account several critical determinants of these parameters. However, two key phases of ESD determine\nthe total procedure time: the mucosal circumference incision speed (CIS) and submucosal dissection speed (SDS). Methods. We\nincluded 302 cases of en bloc and R0 resection of gastric neoplasms performed by 10 operators who had completed the training\nprogramat our hospital. Twelve locationswere classified based onmultiple criteria, such as condition of surroundingmucosa, lesion\nvascularity, presence of submucosal fat, ulcers, scars, fibrosis, and scope and device maneuverability. Lesions in different locations\nwere classified into three groups based on the length of the procedure: fast, moderate, or late. Results. A significant difference was\nfound inCIS and SDS for each location (
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